Growth, pubertal development, and skeletal health in boys with Duchenne Muscular Dystrophy
نویسندگان
چکیده
منابع مشابه
Histological effects of givinostat in boys with Duchenne muscular dystrophy
Duchenne Muscular Dystrophy (DMD) is caused by mutations in the dystrophin gene leading to dystrophin deficiency, muscle fiber degeneration and progressive fibrotic replacement of muscles. Givinostat, a histone deacetylase (HDAC) inhibitor, significantly reduced fibrosis and promoted compensatory muscle regeneration in mdx mice. This study was conducted to evaluate whether the beneficial histol...
متن کاملSocial behavior problems in boys with Duchenne muscular dystrophy.
Duchenne muscular dystrophy (DMD) is a chronic, progressive pediatric disease that affects both muscle and brain. The objectives of the study were to examine parent reported behavior in children with DMD, investigate the influence of chronic illness, intellectual ability and etiology on behavior, and determine whether a specific behavioral profile is associated with DMD. Parental ratings of boy...
متن کاملParental stress in mothers of boys with duchenne muscular dystrophy.
OBJECTIVE To examine parental stress in mothers of boys with Duchenne muscular dystrophy (DMD). METHOD Stress and its predictors were examined in mothers of boys with DMD (n = 112). Comparisons were made with mothers of healthy children (n = 800), children with cerebral palsy (CP; n = 28), siblings of boys with DMD (n = 46), and longitudinally (n = 16). RESULTS The presence of problem child...
متن کاملSleep disorders in boys with Duchenne muscular dystrophy.
AIM Determine the frequency and predictors of sleep disorders in boys with Duchenne Muscular Dystrophy (DMD). METHOD Cross-sectional study by postal questionnaire. Sleep disturbances were assessed using the Sleep Disturbance Scale for Children (validated on 1157 healthy children). A total sleep score and six sleep disturbance factors representing the most common sleep disorders were computed....
متن کاملPoor facial affect recognition among boys with duchenne muscular dystrophy.
Children with Duchenne or Becker muscular dystrophy (MD) have delayed language and poor social skills and some meet criteria for Pervasive Developmental Disorder, yet they are identified by molecular, rather than behavioral, characteristics. To determine whether comprehension of facial affect is compromised in boys with MD, children were given a matching-to-sample test with four types of visual...
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ژورنال
عنوان ژورنال: Current Opinion in Endocrinology & Diabetes and Obesity
سال: 2019
ISSN: 1752-296X
DOI: 10.1097/med.0000000000000456